CD228 antibodies, human

CD228 antibodies, human

Clone: REA717 | Dilution: 1:50
Clone REA717 recognizes the human CD228 antigen, a cell-surface sialoglycoprotein also known as MFI2 or melanotransferrin. CD228 is mainly found in human melanomas, but also in liver, epithelium, and in certain fetal tissues. It plays a role in iron cellular uptake. CD228 is internalized before being recycled back to the cell membrane and is also able to bind zinc.
Additional information: Clone REA717 displays negligible binding to Fc receptors.

Alternative names

Melanotransferrin, MFI2, MAP97, MTF1

Technical specifications

  • Antigen: CD228
  • Clone: REA717
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Melanotransferrin, MFI2, MAP97, MTF1
  • Entrez Gene ID: 4241
  • Molecular mass of antigen [kDa]: 76
  • Distribution of antigen: melanoma, liver, epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, Biotin
  • Selected references

    1. Baker, E. N. et al. (1992) Human melanotransferrin (p97) has only one functional iron-binding site. FEBS Lett. 298(2-3): 215-218
    2. Kennard, M. L. et al. (1995) A novel iron uptake mechanism mediated by GPI-anchored human p97. EMBO J. 14(17): 4178-4186
    3. Suryo Rahmanto, Y. et al. (2007) The melanoma tumor antigen, melanotransferrin (p97): a 25-year hallmark--from iron metabolism to tumorigenesis. Oncogene 26(42): 6113-6124
Product options: 8
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
130-111-408

CD228-PE, human

for 30
tests
(1)
EUR  135,00
130-111-221

CD228-PE, human

for 100
tests
(1)
EUR  315,00
130-111-409

CD228-APC, human

for 30
tests
(1)
EUR  135,00
130-111-222

CD228-APC, human

for 100
tests
(1)
EUR  315,00
for 30
tests
(1)
EUR  110,00
for 100
tests
(1)
EUR  265,00

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