CD158d (KIR2DL4) antibodies, human

CD158d (KIR2DL4) antibodies, human

Clone: REA768 | Dilution: 1:50
Clone REA768 recognizes the human CD158d antigen, a transmembrane glycoprotein belonging to the killer cell immunoglobulin-like receptors (KIR) family, expressed by natural killer (NK) cells and subsets of CD8
+
T cells. KIRs recognize polymorphic human HLA class I molecules and have inhibitory and activation functions. Binding of CD158d to its receptor HLA-G leads to the inhibition of the cytolytic NK cell function.
Additional information: Clone REA768 displays negligible binding to Fc receptors.

Alternative names

KIR2DL4, KIR103AS, 2DL4, p49, KIR103

Technical specifications

  • Antigen: CD158d (KIR2DL4)
  • Clone: REA768
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: KIR2DL4, KIR103AS, 2DL4, p49, KIR103
  • Entrez Gene ID: 3805
  • Molecular mass of antigen [kDa]: 39
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Selvakumar, A. et al. (1996) NK cell receptor gene of the KIR family with two IG domains but highest homology to KIR receptors with three IG domains. Tissue Antigens 48(4 Pt 1): 285-294
    2. Valiante, N. M. et al. (1997) Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity 7(6): 739-751
    3. Goodridge, J. P. et al. (2007) Three common alleles of KIR2DL4 (CD158d) encode constitutively expressed, inducible and secreted receptors in NK cells. Eur. J. Immunol. 37(1): 199-211
Product options: 8
for 30
tests
(1)
EUR  105,00
for 100
tests
(1)
EUR  260,00
for 30
tests
(1)
EUR  125,00
for 100
tests
(1)
EUR  310,00
for 30
tests
(1)
EUR  125,00
for 100
tests
(1)
EUR  310,00
for 30
tests
(1)
EUR  105,00
for 100
tests
(1)
EUR  260,00

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