CD103 antibodies, rat

CD103 antibodies, rat

Clone: REA531 | Dilution: 1:10
Clone REA531 recognizes the rat CD103 antigen, a type I transmembrane protein, which is also known as αE integrin. It associates with integrin β7 to form the heterodimeric integrin molecule αEβ7 and is a receptor for the ligand E-cadherin expressed on epithelial cells. CD103 is expressed by bone marrow–derived dendritic cells and is found on intraepithelial and peripheral lymphocytes, such as regulatory T cell subpopulations. Rat plasmacytoid dendritic cells do not express the dendritic cell–specific marker CD103.
Additional information: Clone REA531 displays negligible binding to Fc receptors.

Alternative names

ITGAE, Integrin aE, HML1, Integrin E

Technical specifications

  • Antigen: CD103
  • Clone: REA531
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: ITGAE, Integrin aE, HML1, Integrin E
  • Entrez Gene ID: 83577
  • Molecular mass of antigen [kDa]: 129
  • Distribution of antigen: T cells, lymphocytes, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Cynthia, S. et al. (2002) Flt-3 ligand (FL) drives differentiation of rat bone marrow-derived dendritic cells expressing OX62 and/or CD161 (NKR-P1). J. Leukoc. Biol. 71: 941-949
    2. Hubert, F. X. et al. (2004)
      Rat plasmacytoid dendritic cells are an abundant subset of MHC Class II
      +
      CD4
      +
      CD11b
      OX62
      and type I IFN-producing cells that exhibit selective expression of Toll-like receptors 7 and 9 and strong responsiveness to CpG.
      J. Immunol. 172(12): 7485-7494
    3. Trinité, B. et al. (2005)
      Immature CD4
      CD103
      +
      rat dendritic cells induce rapid caspase-independent apoptosis-like cell death in various tumor and non tumor cells and phagocytose their victims.
      J. Immunol. 175: 2408-2417
Product options: 8
130-108-208

CD103-FITC, rat

9 µg in 300 µL (1)
EUR  25,00
130-108-182

CD103-FITC, rat

30 µg in 1 mL (1)
EUR  50,00
130-108-209

CD103-PE, rat

9 µg in 300 µL (1)
EUR  32,00
130-108-183

CD103-PE, rat

30 µg in 1 mL (1)
EUR  90,00
130-108-210

CD103-APC, rat

9 µg in 300 µL (1)
EUR  46,00
130-108-184

CD103-APC, rat

30 µg in 1 mL (1)
EUR  90,00
9 µg in 300 µL (1)
EUR  18,00
30 µg in 1 mL (1)
EUR  50,00

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