CD10 antibodies, human

CD10 antibodies, human

Clone: 97C5 | Dilution: 1:50
Clone 97C5 recognizes the human CD10 antigen, the human common acute lymphoblastic leukemia antigen (CALLA). CD10 is a 100 kDa cell surface molecule identical to human membrane-associated neutral endopeptidase (NEP) and also known as neprilysin or enkephalinase. Human CD10 is expressed on a wide variety of normal and neoplastic cell types from different tissues including neural and hematopoietic cells. It is expressed on pre– and pro–B cells and is involved in B cell development and differentiation. The antigen is also present on mature neutrophils, T cell precursors, and some T cell leukemias/lymphomas. Furthermore, CD10 is expressed on neoplastic cells of several B lymphoid leukemias/lymphomas.

Alternative names

MME, CALLA, NEP, SFE, gp100

Technical specifications

  • Antigen: CD10
  • Clone: 97C5
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: MME, CALLA, NEP, SFE, gp100
  • Entrez Gene ID: 4311
  • Molecular mass of antigen [kDa]: 85
  • Distribution of antigen: B cells, bone marrow, brain, epithelial cells, fibroblasts, granulocytes, gut, kidney, leukemia cells, ES and iPS cells, smooth muscle, stromal cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, FITC
  • Selected references

    1. Shipp, M. A. and Look, A. T. (1993) Hematopoietic differentiation antigens that are membrane-associated enzymes: cutting is the key! Blood 82: 1052-1070
    2. Kalled, S. L. et al. (1995) The distribution of CD10 (NEP 24.11, CALLA) in human and mice is similar in non-lymphoid organs but differ within the hematopoietic system: absence on murine T and B lymphoid progenitors. Eur. J. Immunol. 25: 677-687
Product options: 4
130-119-675

CD10-APC, human

for 30
tests
(1)
EUR  125,00
130-119-576

CD10-APC, human

for 100
tests
(1)
EUR  310,00
130-124-262

CD10-FITC, human

for 30
tests
(1)
EUR  105,00
130-124-215

CD10-FITC, human

for 100
tests
(1)
EUR  260,00

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