Anti-TCR Vβ4 antibodies, mouse

Anti-TCR Vβ4 antibodies, mouse

Clone: REA729 | Dilution: 1:50
Clone REA729 recognizes the mouse V beta 4 T cell receptor (TCR Vβ4). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRα/β T cells, though a minority of T cells express an alternate receptor, formed by variable γ and δ chains, referred as TCRγ/δ T cells. TCR Vβ4 is a variant of the TCR β chain and is expressed on mouse strains with the a (e.g., Balb/c), b (e.g., C57BL/6) and c (e.g., SJL, NOD) haplotypes in the Tcrb gene complex.
Additional information: Clone REA729 displays negligible binding to Fc receptors.

Alternative names

TCR Vb4

Technical specifications

  • Antigen: TCR Vβ4
  • Clone: REA729
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TCR Vb4
  • Entrez Gene ID: 100124660
  • Molecular mass of antigen [kDa]: 13
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Singer, P. A. et al. (1988) T-cell receptor alpha-chain variable-region haplotypes of normal and autoimmune laboratory mouse strains. Proc. Natl. Acad. Sci. U.S.A. 85(20): 7729-7733
    2. Tomonari, K. et al. (1990)
      Correlation between the V beta 4
      +
      CD8
      +
      T-cell population and the H-2d haplotype.
      Immunogenetics 31(5-6): 333-339
    3. Sugihara, S. et al. (1993) Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. Characterization of thyroiditis-inducing T cell lines and clones derived from thyroid lesions. J. Immunol. 150(2): 683-694
Product options: 14
30 µg in 200 µL (1)
EUR  50,00
150 µg in 1 mL (1)
EUR  140,00
30 µg in 200 µL (1)
EUR  90,00
150 µg in 1 mL (1)
EUR  265,00
30 µg in 200 µL (1)
EUR  90,00
150 µg in 1 mL (1)
EUR  265,00
30 µg in 200 µL (1)
EUR  120,00
150 µg in 1 mL (1)
EUR  345,00
30 µg in 200 µL (1)
EUR  120,00
150 µg in 1 mL (1)
EUR  345,00
30 µg in 200 µL (1)
EUR  120,00
150 µg in 1 mL (1)
EUR  345,00
30 µg in 200 µL (1)
EUR  50,00
150 µg in 1 mL (1)
EUR  140,00

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