Anti-SSEA-1 antibodies, human and mouse

Anti-SSEA-1 antibodies, human and mouse

Clone: REA321 | Dilution: 1:50
Clone REA321 recognizes the human and mouse stage specific embryonic antigen 1 (SSEA-1) antigen, which is a Lewis blood group related carbohydrate antigen, also known as CD15. SSEA-1 is expressed on human myelomonocytic cells and is present on neutrophils, eosinophils, and some monocytes, but not on basophils or lymphocytes. The antigen is also expressed on Hodgkin/Reed-Sternberg cells. SSEA-1 is a common surface marker for pluripotency on mouse ES and iPS cells. On human cells in contrast, SSEA-1 is expressed only on early differentiating cells.
Additional information: Clone REA321 displays negligible binding to Fc receptors.

Alternative names

FUT4, CD15, ELFT, FCT3A, FUC-TIV, FUTIV, Lex

Technical specifications

  • Antigen: SSEA-1
  • Clone: REA321
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: FUT4, CD15, ELFT, FCT3A, FUC-TIV, FUTIV, Lex
  • Distribution of antigen: monocytes, eosinophils, neutrophils, ES and iPS cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
  • Selected references

    1. Son, M. J. et al. (2009) SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell 4(5): 440-452
    2. Knowles, B. B. et al. (1982) Murine embryonic antigen (SSEA-1) is expressed on human cells and structurally related human blood group antigen I is expressed on mouse embryo. Dev. Biol. 93(1): 54-58
    3. Nudelman, E. et al. (1980) Monoclonal antibody directed to the stage-specific embryonic antigen (SSEA-1) reacts with branched glycosphingolipid similar in structure to Ii antigen. Biochem. Biophys. Res. Commun. 97(2): 443-451
  • Customer reports and application notes

Product options: 2
for 30
tests
(1)
EUR  125,00
for 100
tests
(1)
EUR  310,00

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