Anti-Siglec-F antibodies, mouse

Anti-Siglec-F antibodies, mouse

Clone: REA798 | Dilution: 1:50
Clone REA798 recognizes the mouse siglec-F antigen, also kown as Siglec-5, which belongs to the siglec family (sialic acid-binding immunoglobulin-type lectins). Siglecs are expressed on immune cells and are a subset of the I-type lectins. Siglec-F contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. In mouse, siglec-F is an inhibitory receptor on eosinophils.
Additional information: Clone REA798 displays negligible binding to Fc receptors.

Alternative names

SIGLECF, SIGLEC5, mSiglec-F, Siglec-5

Technical specifications

  • Antigen: Siglec-F
  • Clone: REA798
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: SIGLECF, SIGLEC5, mSiglec-F, Siglec-5
  • Entrez Gene ID: 233168
  • Molecular mass of antigen [kDa]: 60
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Tateno, H. et al. (2005) Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6-sulfo-sialyl Lewis X as a preferred glycan ligand. Glycobiology 15(11): 1125-1135
    2. Zhang, M. et al. (2007)
      Defining the
      in vivo
      function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils.
      Blood 109(10): 4280-4287
    3. Guo, J. P. et al. (2011) Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs. Am. J. Respir. Cell Mol. Biol. 44(2): 238-243
Product options: 14
30 µg in 200 µL (1)
EUR  50,00
150 µg in 1 mL (1)
EUR  140,00
30 µg in 200 µL (1)
EUR  90,00
150 µg in 1 mL (1)
EUR  265,00
30 µg in 200 µL (1)
EUR  90,00
150 µg in 1 mL (1)
EUR  265,00
30 µg in 200 µL (1)
EUR  120,00
150 µg in 1 mL (1)
EUR  345,00
30 µg in 200 µL (1)
EUR  120,00
150 µg in 1 mL (1)
EUR  345,00
30 µg in 200 µL (1)
EUR  120,00
150 µg in 1 mL (1)
EUR  345,00
30 µg in 200 µL (1)
EUR  50,00
150 µg in 1 mL (1)
EUR  140,00

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