Anti-Siglec-8 antibodies, human

Anti-Siglec-8 antibodies, human

Clone: REA1045
Clone REA1045 recognizes siglec-8, a 54 kDa type I transmembrane protein, which is a member of the Ig superfamily. Though it is mainly expressed by eosinophils, expression of siglec-8 is also found on basophils and mast cells. It has been reported that siglec-8 cross-linking with antibodies reduces eosinophil viability through induction of apoptosis.
Additional information: Clone REA1045 displays negligible binding to Fc receptors.

Alternative names

SAF2, SIGLEC8L

Technical specifications

  • Antigen: Siglec-8
  • Clone: REA1045
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: SAF2, SIGLEC8L
  • Entrez Gene ID: 27181
  • Molecular mass of antigen [kDa]: 52
  • Distribution of antigen: basophils, eosinophils, mast cells
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1
100 µg in 100 µL
EUR  195,00