Anti-NK1.1 antibodies, mouse

Anti-NK1.1 antibodies, mouse

Clone: REA1162 | Dilution: 1:50
Clone REA1162 recognizes the mouse NK1.1 antigen, a single-pass type II membrane protein also known as CD161 or killer cell lectin-like receptor subfamily B member 1. NK1.1 is expressed by natural killer cells and a subset of T cells in the mouse strains C57BL/6, FVB/N, and NZB, but not in the mouse strains AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. It plays a stimulatory role on natural killer cells cytotoxicity. Activation by cross-linking of the receptor induces Ca
2+
mobilization and interferon-gamma production.
Additional information: Clone REA1162 displays negligible binding to Fc receptors.

Alternative names

NKR-P1 40, CD161c, Ly-55c, NK1.1, NKR-P1.9, NKR-P1C

Technical specifications

  • Antigen: NK1.1
  • Clone: REA1162
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: NKR-P1 40, CD161c, Ly-55c, NK1.1, NKR-P1.9, NKR-P1C
  • Entrez Gene ID: 17059
  • Molecular mass of antigen [kDa]: 25
  • Distribution of antigen: NK cells, T cells, NKT cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected references

    1. Giorda, R. et al. (1992) Genomic structure and strain-specific expression of the natural killer cell receptor NKR-P1. J. Immunol. 149(6): 1957-1963
    2. Stenström, M. et al. (2005) Natural killer T-cell populations in C57BL/6 and NK1.1 congenic BALB.NK mice-a novel thymic subset defined in BALB.NK mice. Immunology 114(3): 336-345
    3. Ruiz, A. L. et al. (2014)
      NK1.1
      +
      CD8
      +
      T cells escape TGF-β control and contribute to early microbial pathogen response.
      Nat Commun 5: 5150
Product options: 9
30 µg in 200 µL (1)
EUR  70,00
150 µg in 1 mL (1)
EUR  205,00
30 µg in 200 µL (1)
EUR  70,00
30 µg in 200 µL (1)
EUR  120,00
30 µg in 200 µL (1)
EUR  120,00
30 µg in 200 µL (1)
EUR  120,00
30 µg in 200 µL (1)
EUR  170,00
150 µg in 1 mL (1)
EUR  490,00
30 µg in 200 µL (1)
EUR  40,00