Anti-IL-17E antibodies, mouse

Anti-IL-17E antibodies, mouse

Clone: REA952 | Dilution: 1:50
Clone REA952 recognizes the mouse interleukin 17E (IL-17E) antigen. IL-17 is a family of pro-inflammatory cytokines that plays a central role in adaptive immunity as well as autoinflammatory disorders. Data from several mouse models suggest that IL-17 plays a key role in the host defense against certain extracellular bacterial infections. IL-17E is suggested to be an important mediator of allergic disease via production of IL-4, IL-5, IL-13, and eotaxin. IL-17E expression is found in low levels in different peripheral tissues, e.g., prostate, testis, trachea, brain, kidney, and lung.
Additional information: Clone REA952 displays negligible binding to Fc receptors.

Alternative names

IL17E, Interleukin 17E, IL-25, IL25, Interleukin 25

Technical specifications

  • Antigen: IL-17E
  • Clone: REA952
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: IL17E, Interleukin 17E, IL-25, IL25, Interleukin 25
  • Entrez Gene ID: 140806
  • Molecular mass of antigen [kDa]: 18
  • Distribution of antigen: lung, kidney, prostate, trachea, testicle, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
  • Selected references

    1. Fort, M. M. et al. (2001)
      IL-25 induces IL-4, IL-5, and IL-13 and Tʜ2-associated pathologies
      in vivo
      .
      Immunity 15(6): 985-995
    2. Hurst, S. D. et al. (2002)
      New IL-17 family members promote Tʜ1 or Tʜ2 responses in the lung:
      in vivo
      function of the novel cytokine IL-25.
      J. Immunol. 169(1): 443-453
    3. Weaver, C. T. et al. (2007) IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25: 821-852
Product options: 6
30 µg in 200 µL (1)
EUR  50,00
150 µg in 1 mL (1)
EUR  140,00
30 µg in 200 µL (1)
EUR  90,00
150 µg in 1 mL (1)
EUR  265,00
30 µg in 200 µL (1)
EUR  90,00
150 µg in 1 mL (1)
EUR  265,00

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