Anti-FPRL1/FPR2 antibodies, human

Anti-FPRL1/FPR2 antibodies, human

Clone: REA663 | Dilution: 1:11
Clone REA663 recognizes the human FPRL1 antigen, a G-protein coupled receptor (GPCR), also known as FPR2 or N-formyl peptide receptor 2. FPRL1 mediates chemotaxis, degranulation, and the respiratory burst. It interacts with lipoxin A4, which is involved in immunomodulatory and anti-inflammatory actions. FPRL1 is expressed on mononuclear phagocytes and microglial cells.
Additional information: Clone REA663 displays negligible binding to Fc receptors.

Alternative names

FPR2, ALXR, RFP, HM63

Technical specifications

  • Antigen: FPRL1/FPR2
  • Clone: REA663
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: FPR2, ALXR, RFP, HM63
  • Entrez Gene ID: 2358
  • Molecular mass of antigen [kDa]: 39
  • Distribution of antigen: microglia, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, PE-Vio770, APC-Vio770, Biotin, PE
  • Selected references

    1. Murphy, P. M. et al. (1992) A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family. J. Biol. Chem. 267(11): 7637-7643
    2. Takano, T. et al. (1997) Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors. J. Exp. Med. 185(9): 1693-1704
Product options: 8
for 30
tests
(1)
EUR  135,00
for 100
tests
(1)
EUR  315,00
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  110,00
for 100
tests
(1)
EUR  265,00