Anti-EGR-2 antibodies, mouse

Anti-EGR-2 antibodies, mouse

Clone: REA869 | Dilution: 1:50
Clone REA869 recognizes the mouse transcription factor EGR-2, also known as early growth response protein 2 or Krox20. EGR-2 consists of three tandem C2H2-type zinc fingers and its expression is induced by EGFR, which is important for osteoprogenitor maintenance and new bone formation. EGR-2 is found primarily in adult thymus, in the embryonic nervous system, and in mammary tumors and plays a critical role in the development of T cells and NKT cells.
Additional information: Clone REA869 displays negligible binding to Fc receptors.

Alternative names

Egr-2, Krox-20, Krox20, Zfp-25

Technical specifications

  • Antigen: EGR-2
  • Clone: REA869
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Egr-2, Krox-20, Krox20, Zfp-25
  • Entrez Gene ID: 13654
  • Molecular mass of antigen [kDa]: 50
  • Distribution of antigen: T cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Vio515
  • Selected references

    1. Warner, L. E. et al. (1998) Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies. Nat. Genet. 18(4): 382-384
    2. Dillon, R. L. et al. (2007) An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer. Mol. Cell. Biol. 27(24): 8648-8657
    3. Chandra, A. et al. (2013) Epidermal growth factor receptor (EGFR) signaling promotes proliferation and survival in osteoprogenitors by increasing early growth response 2 (EGR2) expression. J. Biol. Chem. 288(28): 20488-20498
Product options: 8
30 µg in 200 µL (1)
EUR  50,00
150 µg in 1 mL (1)
EUR  140,00
30 µg in 200 µL (1)
EUR  90,00
150 µg in 1 mL (1)
EUR  265,00
30 µg in 200 µL (1)
EUR  90,00
150 µg in 1 mL (1)
EUR  265,00
30 µg in 200 µL (1)
EUR  110,00
150 µg in 1 mL (1)
EUR  320,00

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