Anti-DLL1 antibodies, human

Anti-DLL1 antibodies, human

Clone: REA1110 | Dilution: 1:50
Clone REA1110 recognizes the human delta-like protein 1 (DLL1), a type I transmembrane protein expressed by various organs, such as heart, pancreas, brain, muscle, and the hematopetic system; it is relevant for the differentiation of various cell types. In the immune system, DLL1 is required for differentiation of marginal zone B cells and can be expressed by various antigen-presenting cells (APC) contributing to APC-directed peripheral T cell differentiation.
Additional information: Clone REA1110 displays negligible binding to Fc receptors.

Alternative names

Delta1, DL1, Delta, DELT

Technical specifications

  • Antigen: DLL1
  • Clone: REA1110
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Delta1, DL1, Delta, DELT
  • Entrez Gene ID: 28514
  • Molecular mass of antigen [kDa]: 76
  • Distribution of antigen: heart, pancreas, brain, muscle
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio615, PE-Vio770, APC-Vio770, VioBright 515
  • Selected references

    1. Dontja, W. et al. (2006) Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B. Blood 107(6): 2446-2452
    2. Jung, J. et al. (2011) Regulation of Notch1 signaling by Delta-like ligand 1 intracellular domain through physical interaction. Mol. Cell 32(2): 161-165
    3. Andrawes, M. B. et al. (2013) Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1. J. Biol. Chem. 288(35): 25477-25489
Product options: 12
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(1)
EUR  125,00
for 100
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EUR  310,00
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(1)
EUR  125,00
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(1)
EUR  310,00
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(1)
EUR  140,00
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tests
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EUR  335,00
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tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  140,00
for 100
tests
(1)
EUR  335,00
for 30
tests
(1)
EUR  175,00
for 100
tests
(1)
EUR  420,00