Automated cell isolation as easy as it gets
Instrument features
Infinite sample options
Start directly from whole blood, PBMCs, or single cell suspensions
The autoMACS Pro Separator is compatible with hundreds of MACS Cell Separation Reagents for easy and fast isolation of virtually any cell type from any species and tissue, such as:
- Peripheral blood mononuclear cells (PBMCs)
- Whole blood or bone marrow
- Single-cell suspensions e.g. from dissociated spleens or lymph nodes
- Other dissociated tissues e.g. tumors
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Supporting various applications
By providing maximum flexibility in terms of starting materials, the autoMACS Pro Separator can be used for a variety of applications.
For example, the isolation of CD14+ cells directly from whole blood or bone marrow using StraightFrom™ Whole Blood CD14 MicroBeads, human allows for standardized isolation of monocytes and macrophages. CD14+ cells, isolated with the autoMACS Pro Separator are well-suited for further flow cytometric, molecular or functional analyses, such as proliferation and activation assays.
Find more applications here.
Walk-away automation
Autolabeling of multiple samples
The autoMACS Pro Separator allows automated labeling of cells with magnetic MACS® MicroBeads. The MACS Reagent Rack can accomodate up to four reagent vials. Using the barcode reader, MACS Reagents can be scanned and the instrument automatically selects the appropiate separation program.
Automated magnetic cell isolation
Cell isolation at the click of a button: After starting the respective separation program, the autoMACS Pro Separator performs walk-away cell isolation including automated startup, cleaning, and shutdown. On top, it allows safe laboratory practices when dealing with hazardous samples
Parallel sample processing: Up to 6 samples can be processed in a single run, while keeping them cooled on a MACS Chill Rack. This saves you time, is reliable, and delivers reproducible results.
Sensor-controlled processes: The autoMACS constantly monitors the instrument status, buffer levels, and column status. This ensures optimal performance and safety of your samples.
Target cells ready for downstream applications: Cells purified using the autoMACS Pro Separator are well-suited for further flow cytometric analysis, molecular biology studies, and functional studies.
Parallel sample processing: Up to 6 samples can be processed in a single run, while keeping them cooled on a MACS Chill Rack. This saves you time, is reliable, and delivers reproducible results.
Sensor-controlled processes: The autoMACS constantly monitors the instrument status, buffer levels, and column status. This ensures optimal performance and safety of your samples.
Target cells ready for downstream applications: Cells purified using the autoMACS Pro Separator are well-suited for further flow cytometric analysis, molecular biology studies, and functional studies.
One column fits all
One autoMACS Column for all cell isolation strategies
The reusable autoMACS Column is specifically designed for use with the autoMACS Pro Separator delivering high cell purities and recoveries. Whether performing positive selection, depletion, or untouched isolations, this column fits all your cell isolation needs.
Once installed, the columns become part of a closed fluidic system that keeps you safe when dealing with hazardous samples. Monitoring and priming of the column is automatically managed by the instrument software.
Once installed, the columns become part of a closed fluidic system that keeps you safe when dealing with hazardous samples. Monitoring and priming of the column is automatically managed by the instrument software.
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Sample cooling
MACS Chill Racks
Maintain the integrity of your valuable samples by keeping your cells at 4° C. MACS® Chill Racks allow up to 6 samples to be processed in a single batch. The flexible format is compatible with 50 mL, 15 mL, or 5 mL tubes.
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The autoMACS Pro Separator is highly time-saving, while providing a fast, reproducible, and cell friendly cell separation. With small modifications, even better purities can be obtained compared to manual separation.
Experimental Hematology Research Group
Clinic and Policlinic for Pediatrics, University Medical Center Carl Gustav Carus, Dresden
The research group uses their autoMACS Pro Separator for the isolation of human and murine HSCs, T cells, and dendritic cells. They perform both positive and negative selection strategies with important markers such as BDCA2, BDCA4, CD4, CD8, CD11b, CD105 and a lineage-panel. After cell separation, cells are used for in vivo (e.g. transplantation) and in vitro (e.g. co-culture, stimulation, and analysis) experiments.
