CD8 MicroBead Kit, non-human primate

CD8 MicroBead Kit, non-human primate

The CD8 MicroBead Kit was developed for the positive selection or depletion of CD8
+
cells from rhesus monkey PBMCs.

Background information

CD8 is expressed on rhesus monkey cytotoxic T cells as well as on a subset of NK cells. The CD8 MicroBead Kit consists of a monoclonal CD8 antibody conjugated to phycoerythrin (CD8-PE) and Anti-PE MicroBeads.

Downstream applications

The kit has been used in the context of developing an
in vitro
viral suppression assay.
1
It has also been used to investigate T lymphocyte subset responsiveness to vaccine regimens.
2

Columns

For positive selection: MS, LS, XS, or autoMACS
®
Columns. For depletion: LD, D, or autoMACS Columns.
  • Selected references

    1. Loffredo, J. T. et al. (2005)
      Tat(28-35)SL8-specific CD8
      +
      T lymphocytes are more effective than Gag(181-189)CM9-specific CD8
      +
      T lymphocytes at suppressing simian immunodeficiency virus replication in a functional
      in vitro
      assay.
      J. Virol. 79: 14986-14991
    2. Santra, S. et al. (2005) Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates. J. Virol. 79: 6516-6522
Product options: 1
for 1×
10
9
total cells
EUR  697,00

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