Specifications for Ly-49G2 Antibody, anti-mouse, REAfinity™
Overview
Clone REA1053 recognizes Ly-49G2, which is a inhibitory receptor specific for class Ia MHC molecules. Ly-49G2 belongs to the Ly-49 multigene family, which consists of type II transmembrane homodimeric receptors. Inhibitory Ly-49 members such as Ly-49G2 contain immunoreceptor tyrosine-based inhibitory motif (ITIM) 3 in their cytoplasmic tail and transduce signal that prevents the NK cell cytolytic activity upon recognizing ligands such as H-2Ddk. Expression of Ly-49G2 is found on subsets of natural killer (NK) cells, NK-T cells, and on a population of memory CD8
+ T cells (in C57BL/6 mice).
Additional information: Clone REA1053 displays negligible binding to Fc receptors
Alternative names
Klra7, LGL-1, Ly49G.4, Ly-49G, Ly49g1, Ly-49G2Detailed product information
Technical specifications
| Clone | REA1053 |
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| Clonality | monoclonal |
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| Isotype | recombinant human IgG1 |
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| Isotype control | REA Control Antibody, human IgG1 |
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| Host | human cell line |
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| Type of antibody | Primary antibodies, Recombinant antibodies |
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| Species | mouse |
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| Antigen | Ly-49G2 |
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| Alternative names of antigen | Klra7, LGL-1, Ly49G.4, Ly-49G, Ly49g1, Ly-49G2 |
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| Molecular mass of antigen [kDa] | 33 |
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| Distribution of antigen | NK cells |
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| Entrez Gene ID | 16638 |
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| RRID | AB_2733602, AB_2733739, AB_2733740, AB_2751443, AB_2733320, AB_2732944, AB_2732945, AB_2921720, AB_2733994, AB_2733995, AB_2733484, AB_2733485, AB_2733601 |
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