Clone:
REAL1128
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
c-Jun N-terminal kinase 1, MAP kinase 8, JNK-46, SAPK1c, SAPK1, PRKM8

Specifications for JNK1 (MAPK8) Antibody, anti-human, REAdye_lease™

Overview

Clone REAL1128 is an antibody fragment derived from the full JNK1 (MAPK8) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL 1128 recognizes JNK1 (MAPK8), also known as c-Jun N-terminal kinase 1 belongs to the MAPK superfamily of stress-activated protein kinasesis. It is involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. JNK1/MAPK8 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

c-Jun N-terminal kinase 1, MAP kinase 8, JNK-46, SAPK1c, SAPK1, PRKM8

Detailed product information

Technical specifications

CloneREAL1128
Clonalitymonoclonal
Isotype controlControl Antibody
Hosthuman cell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenJNK1 (MAPK8)
Alternative names of antigenc-Jun N-terminal kinase 1, MAP kinase 8, JNK-46, SAPK1c, SAPK1, PRKM8
Distribution of antigenT cells
RRIDAB_2905303

Resources for JNK1 (MAPK8) Antibody, anti-human, REAdye_lease™

Certificates

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References for JNK1 (MAPK8) Antibody, anti-human, REAdye_lease™

Publications

  1. Liu, J. et al. (2019) JNK1/2 represses Lkb1-deficiency-induced lung squamous cell carcinoma progression. Nat Commun. 10(1): 2148-doi 10.103
  2. Lorenzati, M. et al. (2021) c-Jun N-terminal kinase 1 (JNK1) modulates oligodendrocyte progenitor cell architecture, proliferation and myelination. Sci Rep 11: 7264

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