Clone:
REA571
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
CANDF9, IL17-RL

Specifications for IL-17RC Antibody, anti-human, REAfinity™

Overview

Clone REA571 recognizes the human IL-17RC antigen, a single-pass transmembrane protein belonging to the IL-17 cytokine family. The IL-17 receptor (IL-17R) subfamily includes IL-17RA, IL-17RB, IL-17RC, IL-17RD, and IL-17RE that induce signaling via recruitment of signaling intermediates. Together with IL-17RA IL-17RC is able to form a receptor complex capable specific for IL-17A and IL-17F. IL-17RC is expressed in prostate and prostate cancer, skeletal muscle, kidney, and placenta.
Additional information: Clone REA571 displays negligible binding to Fc receptors.

Alternative names

CANDF9, IL17-RL

Detailed product information

Technical specifications

CloneREA571
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenIL-17RC
Alternative names of antigenCANDF9, IL17-RL
Molecular mass of antigen [kDa]84
Distribution of antigenprostate cancer cells, kidney, placenta, skeletal muscle
Entrez Gene ID84818
RRIDAB_2652375, AB_2652376, AB_2652377, AB_2652378, AB_2652379, AB_2652380, AB_2652381, AB_2652374

Resources for IL-17RC Antibody, anti-human, REAfinity™

References for IL-17RC Antibody, anti-human, REAfinity™

Publications

  1. Kuestner, R. E. et al. (2007) Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F. J. Immunol. 179(8): 5462-5473
  2. Toy, D. et al. (2006) Cutting edge: interleukin 17 signals through a heteromeric receptor complex. J. Immunol. 177(1): 36-39
  3. Haudenschild, D. et al. (2002) Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer. J. Biol. Chem. 277(6): 4309-4316
  4. Ho, A. W. et al. (2010) IL-17RC: a partner in IL-17 signaling and beyond. Semin. Immunol. 32(1): 33-42

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