Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:

Specifications for IL-17F Antibody, anti-mouse, REAfinity™


Clone REA666 recognizes the mouse interleukin 17F (IL-17F) antigen, a cytokine which is expressed by a subset of activated T cells in the lamina propria. IL-17F belongs to the IL-17 gene family, which consists of six members (IL-17A, IL-17B, IL-17C, IL-17D, IL-17E, and IL-17F). All members have a similar protein structure, with four highly conserved cysteine residues critical to their 3-dimensional shape. The isoforms of IL-17F 1 and 2 (ML-1) have the highest homology to IL-17A. It has been reported, that IL-17–producing T lymphocytes comprise a distinct lineage of proinflammatory T helper cells, termed Tʜ17 cells, that are major contributors to autoimmune disease. IL-17F plays a role in the induction of neutrophilia in the lungs and in the exacerbation of Ag-induced pulmonary inflammation.
Additional information: Clone REA666 displays negligible binding to Fc receptors.

Alternative names


Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Alternative names of antigenInterleukin-17F
Molecular mass of antigen [kDa]15
Distribution of antigenT cells
Entrez Gene ID257630
RRIDAB_2652365, AB_2652366, AB_2652367, AB_2652364

Resources for IL-17F Antibody, anti-mouse, REAfinity™


Please follow this
to search for Certificates of Analysis (CoA) by lot number.

References for IL-17F Antibody, anti-mouse, REAfinity™


  1. Ivanov, I. I. et al. (2006)
    The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17
    T helper cells.
    Cell 126: 1121-1133
  2. Suzuki, S. et al. (2007) Expression of interleukin-17F in a mouse model of allergic asthma. Int. Arch. Allergy Immunol. 143: 89-94
  3. Oda, N. et al. (2005) Interleukin-17F induces pulmonary neutrophilia and amplifies antigen-induced allergic response. Am J Respir Crit Care Med. 171(1): 12-18

Related products for
IL-17F Antibody, anti-mouse, REAfinity™

4 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?