Clone:
REA952
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
IL17E, Interleukin 17E, IL-25, IL25, Interleukin 25

Specifications for IL-17E Antibody, anti-mouse, REAfinity™

Overview

Clone REA952 recognizes the mouse interleukin 17E (IL-17E) antigen. IL-17 is a family of pro-inflammatory cytokines that plays a central role in adaptive immunity as well as autoinflammatory disorders. Data from several mouse models suggest that IL-17 plays a key role in the host defense against certain extracellular bacterial infections. IL-17E is suggested to be an important mediator of allergic disease via production of IL-4, IL-5, IL-13, and eotaxin. IL-17E expression is found in low levels in different peripheral tissues, e.g., prostate, testis, trachea, brain, kidney, and lung.
Additional information: Clone REA952 displays negligible binding to Fc receptors.

Alternative names

IL17E, Interleukin 17E, IL-25, IL25, Interleukin 25

Detailed product information

Technical specifications

CloneREA952
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenIL-17E
Alternative names of antigenIL17E, Interleukin 17E, IL-25, IL25, Interleukin 25
Molecular mass of antigen [kDa]18
Distribution of antigenbrain, testicle, kidney, lung, prostate
Entrez Gene ID140806
RRIDAB_2727178, AB_2727201, AB_2727180, AB_2727200, AB_2727179, AB_2727199

Resources for IL-17E Antibody, anti-mouse, REAfinity™

References for IL-17E Antibody, anti-mouse, REAfinity™

Publications

  1. Fort, M. M. et al. (2001)
    IL-25 induces IL-4, IL-5, and IL-13 and Tʜ2-associated pathologies
    in vivo
    .
    Immunity 15(6): 985-995
  2. Hurst, S. D. et al. (2002)
    New IL-17 family members promote Tʜ1 or Tʜ2 responses in the lung:
    in vivo
    function of the novel cytokine IL-25.
    J. Immunol. 169(1): 443-453
  3. Weaver, C. T. et al. (2007) IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25: 821-852

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