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IL-25 stands for interleukin 25. It is also known as IL-17E. Human IL-25 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.
Applications
Human IL-25 can be used for a variety of applications including:
Tʜ2 differentiation.
ILC stimulation.
Eosinophil differentiation.
Alternative names
IL-17E
Detailed product information
Background information
Interleukin 25 (IL-25) is also known as IL-17E and belongs to the IL-17 family and is secreted by Tʜ2 cells and mast cells. It induces the production of other cytokines by Tʜ2 cells and ILCs, including IL-4, IL-5, and IL-13 in multiple tissues. IL-25 is an important cytokine controlling the immunity of the gut and can be involved in chronic inflammation associated with the gastrointestinal tract. It is also involved in allergic airway inflammation and airway hyper reactivity. In addition it shows anti-tumor activity
in vivo
in several human cancers including melanoma, breast, and lung.
Biological activity
Induction of IL-8 in human PBMCs
Quality description
Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.
IL-25 stands for interleukin 25. It is also known as IL-17E. Human IL-25 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.
Applications
Human IL-25 can be used for a variety of applications including:
Tʜ2 differentiation.
ILC stimulation.
Eosinophil differentiation.
Alternative names
IL-17E
Detailed product information
Background information
Interleukin 25 (IL-25) is also known as IL-17E and belongs to the IL-17 family and is secreted by Tʜ2 cells and mast cells. It induces the production of other cytokines by Tʜ2 cells and ILCs, including IL-4, IL-5, and IL-13 in multiple tissues. IL-25 is an important cytokine controlling the immunity of the gut and can be involved in chronic inflammation associated with the gastrointestinal tract. It is also involved in allergic airway inflammation and airway hyper reactivity. In addition it shows anti-tumor activity
in vivo
in several human cancers including melanoma, breast, and lung.
Biological activity
Induction of IL-8 in human PBMCs
Quality description
Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.
