Clone:
REA857
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
H2

Extended validation for H-2 Antibody, anti-mouse, REAfinity™

Specificity

Epitope competition
In order to compare the epitope specificity of an antibody, the clone being used is compared with other known clones recognizing the same antigen in a competition assay.
Other clonesOverlap in epitope recognition with REA857
M1/42++
Cells were incubated with an excess of purified unconjugated H-2 (REA857) antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or completely different epitopes (-) of the marker.

Specifications for H-2 Antibody, anti-mouse, REAfinity™

Overview

Clone REA857 recognizes the mouse major histocompatibility complex (MHC) class I alloantigen H-2, which is found on nucleated cells from mice having the a, b, d, j, k, s, and u haplotypes. MHC class I molecules, which have an immunoglobulin-like structure and consists of β2 subunits, bind peptide fragments derived from pathogens and present them CD8
+
cytotoxic T cells.
Additional information: Clone REA857 displays negligible binding to Fc receptors.

Alternative names

H2

Detailed product information

Technical specifications

CloneREA857
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenH-2
Alternative names of antigenH2
Molecular mass of antigen [kDa]39
Distribution of antigennucleated cells
Entrez Gene ID83772, 14964, 14972, 14980
RRIDAB_2651907, AB_2651908, AB_2651909, AB_2651910, AB_2651911, AB_2651912, AB_2651913, AB_2651914, AB_2651915, AB_2651916, AB_2651917, AB_2651918, AB_2651919, AB_2651906

Resources for H-2 Antibody, anti-mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

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H-2 Antibody, anti-mouse, REAfinity™

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