Clone REAL828 is an antibody fragment derived from the full GCDFP-15 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL828 recognizes the GCDFP-15 (gross cystic disease fluid protein 15), also known as Prolactin-inducible protein, extra-parotid glycoprotein (EP-GP), gp17 seminal actin-binding protein (SABP) or BRST2. In humans it is encoded by the PIP gene and is upregulated by prolactin and androgens and downregulated by estrogen. GCDFP-15 has various physiological functions and is used as a detection and diagnostic marker of breast cancer cells.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).
