FeraSpin R is a nanoparticulate superparamagnetic iron oxide contrast agent specifically formulated for pre-clinical magnetic resonance imaging (MRI).
It is a contrast agent of high relaxivity enhancing the contrast in T2- and T2*-weighted MRI due to a shortening of the spin-spin relaxation time (T2).
Upon intravenous injection, FeraSpin R is rapidly taken up by the Kupffer cells (macrophages of the liver) resulting in a short blood half-life of a few minutes. FeraSpin R accumulates particularly in the liver and spleen and is degraded with its iron being transferred into the physiological iron

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