CliniMACS® Plus Instrument 
Automated cell separation for clinical-scale cell enrichment or depletion

The user-friendly key components of the CliniMACS® Plus Instrument offer sophisticated applications for a whole variety of separations. The selected stem cells, monocytes, DCs, NK cells, B cells, and T cell subsets allow research in the field of regenerative medicine, adoptive immunotherapy, and graft engineering. 

Cells are magnetically labeled in the Cell Preparation Bag using an antigen-specific reagent. Subsequently, the Cell Preparation Bag is connected to the CliniMACS Plus Instrument. Intuitive software facilitates target cell enrichment or depletion as well as final collection in the Cell Collection Bag. The CliniMACS System separates large numbers of cells providing target cells with high purity and excellent yield. A range of tubing sets optimized for different applications is available. 



Variety of cell separation strategies available – for high purity and excellent yield

Certified medical device

Functionally closed system, compatible for use in a GMP setting

Well-established technology

Tried and tested for more than 20 years

Easy to use

Automated cell separation for reproducible processes

Features & specifications

The CliniMACS® CD34 Reagent System

The CliniMACS® CD34 Reagent System is a medical device that enables in vitro enrichment of CD34-positive hematopoietic stem cells for graft-versus-host disease (GVHD) prophylaxis in patients with AML. Watch the video to learn more.


A wide variety of automated cell separation applications are supported by the CliniMACS Plus System. If your workflow of interest is not highlighted below, please visit our clinical application page.


Technical and field service support 

Comprehensive service options ensure maximum performance of the CliniMACS Plus Instruments over time. 

We provide the necessary official documentation for installation and operational qualifications required to maintain GMP standards. 

CliniMACS Plus Instrument

Automated cell separation for clinical-scale enrichment or depletion
Order no. 151-01

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