The CD1c (BDCA-1) antigen belongs to the CD1 family and is involved in presentation of lipid antigens. In human blood, CD1c (BDCA-1) is exclusively expressed on CD11c
high
CD123
low
myeloid dendritic cells and a small subpopulation of CD19
+
B cells.
1
Myeloid dendritic cells represent the major subset of dendritic cells in human peripheral blood (about 0.3% of white blood cells). They display a strong T cell stimulatory and cross-presenting capacity.
2–4
The CliniMACS CD1c (BDCA-1)-Biotin Product Line consists of murine anti-CD1c (BDCA-1) monoclonal antibodies conjugated to biotin.
One vial contains 5 mL

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CD1c (BDCA-1) Product Line

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