CD8 MicroBead Kit, non-human primate

Name: CD8 MicroBead Kit, non-human primate
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CD8 MicroBead Kit, non-human primate

The CD8 MicroBead Kit was developed for the positive selection or depletion of CD8

⁺

cells from rhesus monkey PBMCs.

Product data and images for CD8 MicroBead Kit, non-human primate

Figures

Figure 1

Separation of CD8

⁺

cells from rhesus monkey PBMCs using the CD8 MicroBead Kit, a MiniMACS™ Separator, and an MS Column.

PBMCs before separation	CD8 ^- cells
View details CD8 MicroBead Kit, non-human primate Figure 1 Separation of CD8 ⁺ cells from rhesus monkey PBMCs using the CD8 MicroBead Kit, a MiniMACS™ Separator, and an MS Column.	View details CD8 MicroBead Kit, non-human primate Figure 1 Separation of CD8 ⁺ cells from rhesus monkey PBMCs using the CD8 MicroBead Kit, a MiniMACS™ Separator, and an MS Column.
CD8 ⁺ cells
View details CD8 MicroBead Kit, non-human primate Figure 1 Separation of CD8 ⁺ cells from rhesus monkey PBMCs using the CD8 MicroBead Kit, a MiniMACS™ Separator, and an MS Column.

Specifications for CD8 MicroBead Kit, non-human primate

Overview

The CD8 MicroBead Kit was developed for the positive selection or depletion of CD8

⁺

cells from rhesus monkey PBMCs.

Detailed product information

Background information

CD8 is expressed on rhesus monkey cytotoxic T cells as well as on a subset of NK cells. The CD8 MicroBead Kit consists of a monoclonal CD8 antibody conjugated to phycoerythrin (CD8-PE) and Anti-PE MicroBeads.

Downstream applications

The kit has been used in the context of developing an

in vitro

viral suppression assay.

¹

It has also been used to investigate T lymphocyte subset responsiveness to vaccine regimens.

²

Columns

For positive selection: MS, LS, XS, or autoMACS

^®

Columns. For depletion: LD, D, or autoMACS Columns.

References for CD8 MicroBead Kit, non-human primate

Publications

Loffredo, J. T. et al. (2005)
Tat(28-35)SL8-specific CD8
⁺
T lymphocytes are more effective than Gag(181-189)CM9-specific CD8
⁺
T lymphocytes at suppressing simian immunodeficiency virus replication in a functional
in vitro
assay.
J. Virol. 79: 14986-14991
Santra, S. et al. (2005) Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates. J. Virol. 79: 6516-6522

Data and images