Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:
Ox-44, TSPAN25

Specifications for CD53 Antibody, anti-rat, REAfinity™


Clone REA512 recognizes the rat CD53 antigen, also known as Ox-44, a 43 kDa glycoprotein and a member of the tetraspanin family, which has four transmembrane domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. CD53 is expressed on almost all hematopoietic cells such as B cells, monocytes, macrophages, neutrophils, und T cells, but not on erythrocytes and platelets.
Additional information: Clone REA512 displays negligible binding to Fc receptors.

Alternative names

Ox-44, TSPAN25

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Alternative names of antigenOx-44, TSPAN25
Molecular mass of antigen [kDa]24
Distribution of antigenB cells, macrophages, monocytes, T cells, neutrophils
Entrez Gene ID24251
RRIDAB_2658669, AB_2658670, AB_2658671, AB_2658672, AB_2658673, AB_2658674, AB_2658675, AB_2658676, AB_2658677, AB_2658678, AB_2658679, AB_2658668

Resources for CD53 Antibody, anti-rat, REAfinity™


Please follow this
to search for Certificates of Analysis (CoA) by lot number.

References for CD53 Antibody, anti-rat, REAfinity™


  1. Tomlinson, M. G. (1993) Epitope mapping of anti-rat CD53 monoclonal antibodies. Implications for the membrane orientation of the Transmembrane 4 Superfamily. Eur. J. Immunol. 23(1): 136-140
  2. Lazo, P. A. et al. (1997) Ligation of CD53/OX44, a tetraspan antigen, induces homotypic adhesion mediated by specific cell-cell interactions. Cell. Immunol. 178(2): 132-140
  3. Bellacosa, A. (1991) The rat leukocyte antigen MRC OX-44 is a member of a new family of cell surface proteins which appear to be involved in growth regulation. Mol. Cell. Biol. 11(5): 2864-2872

Related products for
CD53 Antibody, anti-rat, REAfinity™

2 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?