CD33 antibodies
Clone:
AC104.3E3
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1
Alternative names:
My9, p67, Siglec-3

Specifications for CD33 antibodies

Overview

AC104.3E3 recognizes the human CD33 antigen, a 67 kDa glycoprotein belonging to the sialoadhesin superfamily. The CD33 antigen is highly expressed on human monocytes but weakly on granulocytes and some – but not all – myeloid dendritic cells. The CD33 antigen is also found on myeloid progenitor cells (CFU-GEMM, CFU GM, CFU-G, BFU-E) but is not expressed on lymphocytes, platelets, erythrocytes, or primitive hematopoietic stem cells.

Alternative names

My9, p67, Siglec-3

Detailed product information

Technical specifications

CloneAC104.3E3
Isotypemouse IgG1
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD33
Alternative names of antigenMy9, p67, Siglec-3
Molecular mass of antigen [kDa]38
Distribution of antigendendritic cells, granulocytes, Langerhans cells, macrophages, mast cells, monocytes, NK cells, T cells

Resources for CD33 antibodies

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD33 antibodies

Publications

  1. Bernstein, I. D. et al. (1987)
    Treatment of acute myeloid leukemia cells
    in vitro
    with a monoclonal antibody recognizing a myeloid differentiation antigen allows normal progenitor cells to be expressed.
    J. Clin. Invest. 79(4): 1153-1159
  2. Stelzer, G. T. et al. (1997) U.S.-Canadian consensus recommendations on the immunophenotypic analysis of hematologic neoplasia by flow cytometry: standardization and validation of laboratory procedures. Cytometry 30(5): 214-230
  3. Rothe, G et al. (2012) Consensus protocol for the flow cytometric Immunophenotyping of hematopoietic malignancies. Leukemia 10(5): 877-895
  4. van Dongen, J. J. M. et al. (2012) EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes. Leukemia 26(9): 1908-1975
  5. Clinical and Laboratory Standards Institute (CLSI) (2007) Clinical Flow Cytometric Analysis of Neoplastic Hematolympoid Cells, CLSI document H43-A2 (ISBN 1-56238-635-2). CLSI; Approved Guideline - Second Edition
  6. Clinical and Laboratory Standards Institute (CLSI) (2007) Enumeration of immunologically defined cell populations by flow cytometry, CLSI document H42-A2 (ISBN 1-56238-640-9). CLSI; Approved Guideline - Second Edition
  7. Wood, B. L. et al. (2007) 2006 Bethesda International Consensus recommendations on the immunophenotypic analysis of hematolymphoid neoplasia by flow cytometry: optimal reagents and reporting for the flow cytometric diagnosis of hematopoietic neoplasia. Cytometry B Clin. Cytom. 72: 14-22

Seems like you are coming from USA!
Do you want to visit our website in your country?

Copyright © 2023 Miltenyi Biotec and/or its affiliates. All rights reserved.