CD300e (IREM-2) Antibody, anti-human
Clone:
UP-H2
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC
Alternative names:
CD300LE, CLM-2, CMRF35-A5, IREM-2, PIgR-2, LMIR6

Specifications for CD300e (IREM-2) Antibody, anti-human

Overview

The monoclonal antibody UP-H2 reacts with human CD300e, also known as IREM-2, LMIR6, or CMRF35-A5. This 34 kDa activating receptor of the immunglobulin superfamily is expressed on mature myeloid dendritic cells and monocytes and is down-regulated on immature dendritic cells. CD300e interacts with DAP-12, which mediates acivating signals. It is reported that the alloreactive response of naive T cells is enhanced by IREM-2 activation of mDCs.

Alternative names

CD300LE, CLM-2, CMRF35-A5, IREM-2, PIgR-2, LMIR6

Detailed product information

Technical specifications

CloneUP-H2
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD300e (IREM-2)
Alternative names of antigenCD300LE, CLM-2, CMRF35-A5, IREM-2, PIgR-2, LMIR6
Distribution of antigendendritic cells, monocytes
RRIDAB_2801843, AB_2657138, AB_2657139, AB_2657140, AB_2657141, AB_2657144, AB_2657145, AB_2657146, AB_2657147, AB_2657148, AB_2657149, AB_2657150, AB_2657151, AB_2657152, AB_2657153, AB_2801847

Resources for CD300e (IREM-2) Antibody, anti-human

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD300e (IREM-2) Antibody, anti-human

Publications

  1. Aguilar, H. et al. (2004) Molecular characterization of a novel immune receptor restricted to the monocytic lineage. J Immunol 173: 6703-6711
  2. Brckalo, T. et al. (2010) Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells. Eur. J. Immunol. 40(3): 722-732

Related products for
CD300e (IREM-2) Antibody, anti-human

4 products available
 

Tandem Signal Enhancer, human

The Tandem Signal Enhancer, human increases binding specificity of tandem dye–conjugated antibodies ...

 

Isotype Control Antibody, mouse IgG1

The Mouse IgG1 isotype control antibody clone IS5-21F5 is specific for keyhole limpet hemocyanin ...

130-059-901

FcR Blocking Reagent, human

The FcR Blocking Reagent was developed to increase the specificity of immunofluorescent staining ...

130-097-900

MACS
®
Comp Bead Kit, anti-mouse Igκ

The MACS® Comp Bead Kits have been developed for optimal compensation of the fluorescence spillover ...

Seems like you are coming from USA!
Do you want to visit our website in your country?

Copyright © 2023 Miltenyi Biotec and/or its affiliates. All rights reserved.