Clone:
REA217
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC, MC
Alternative names:
ATP1B3, ATPB-3

Specifications for CD298 Antibody, anti-human, REAfinity™

Overview

Clone REA217 recognizes CD298, the β3 subunit isoform of Na
+
, K
+
-ATPase, which is a membrane associated enzyme. Na
+
, K
+
-ATPase transports Na
+
and K
+
by coupling the hydrolysis of ATP to the transport of Na
+
and K
+
. The movement of ions across the plasma membrane generates and maintains the electrochemical gradient required for osmoregulation, transport of molecules and nutrients. Na
+
, K
+
-ATPase consists of large catalytic α subunit and a smaller glycoprotein non-catalytic β subunit, which exists in three known isoforms.
Additional information: Clone REA217 displays negligible binding to Fc receptors.

Alternative names

ATP1B3, ATPB-3

Detailed product information

Technical specifications

CloneREA217
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD298
Alternative names of antigenATP1B3, ATPB-3
Distribution of antigenleukocytes
RRIDAB_2819459, AB_2801910, AB_2657034, AB_2657035, AB_2657036, AB_2657037, AB_2657038, AB_2657039, AB_2657040, AB_2657041, AB_2657042, AB_2657043, AB_2657044, AB_2657045, AB_2819474

Resources for CD298 Antibody, anti-human, REAfinity™

References for CD298 Antibody, anti-human, REAfinity™

Publications

  1. Jørgensen, P. L. et al. (1982)
    Mechanism of the Na
    +
    , K
    +
    pump. Protein structure and conformations of the pure (Na
    +
    , K
    +
    )-ATPase.
    Biochim. Biophys. Acta 694(1): 27-68
  2. Malik, N. et al. (1996) Identification of the mammalian Na,K-ATPase 3 subunit. J. Biol. Chem. 271(37): 22754-22758
  3. Chiampanichayakul, S. et al. (2006) Na, K ATPase beta3 subunit (CD298): association with alpha subunit and expression on peripheral blood cells. Tissue Antigens 68(6): 517-509

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