Clone:
TS2/16
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC, MICS, IF, IHC
Alternative names:
ITGB1, FNRB, GPIIa, MDF2, MSK12, VLA-BETA, VLAB

Extended validation for CD29 Antibody, anti-human

Specificity

Epitope competition
In order to compare the epitope specificity of an antibody, the clone being used is compared with other known clones recognizing the same antigen in a competition assay.
Other clonesOverlap in epitope recognition with TS2/16
REA1060++
MAR4-
HUTS-21-
4B7R-
Cells were incubated with an excess of purified unconjugated CD29 (TS2/16) antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or completely different epitopes (-) of the marker.

Specifications for CD29 Antibody, anti-human

Overview

Clone TS2/16 reacts with CD29, a 130 kDa single-pass type I membrane protein. CD29 is also known as integrin β1 or GPIIa. It forms heterodimers with integrins α1-11 and αV to form functional integrin receptors which bind several cell surface and extracellular molecules such as collagen, fibronectin, laminin, VCAM1, cytotactin, osteopontin, epiligrin, thrombospondin, etc. The cytoplasmic domain of CD29 can interact with cytoskeletal proteins and signaling molecules. In humans, CD29 can be found in four different isoforms (β1A, β1B, β1C, β1D).

Alternative names

ITGB1, FNRB, GPIIa, MDF2, MSK12, VLA-BETA, VLAB

Detailed product information

Technical specifications

CloneTS2/16
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD29
Alternative names of antigenITGB1, FNRB, GPIIa, MDF2, MSK12, VLA-BETA, VLAB
RRIDAB_2819511, AB_2656998, AB_2656999, AB_2657000, AB_2657001, AB_2657002, AB_2657003, AB_2657004, AB_2657005, AB_2657006, AB_2657007, AB_2819546

Reviews for CD29 Antibody, anti-human

Great CD29 Antibody from Miltenyi Biotec

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CD29-FITC, human (130-101-256)

Will buy and use it again. Recommendable!

References for CD29 Antibody, anti-human

Publications

  1. Brakebusch, C. et al. (1997) Genetic analysis of beta1 integrin function: confirmed, new and revised roles for a crucial family of cell adhesion molecules. J. Cell. Sci. 110: 2895-2904
  2. Altruda, F. et al. (1990) A human integrin beta 1 subunit with a unique cytoplasmic domain generated by alternative mRNA processing. Gene 95: 261-266
  3. Shih, D. T. et al. (1993) Structure/function analysis of the integrin beta 1 subunit by epitope mapping. J. Cell Biol. 122(6): 1361-1371

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