Specifications for CD269 (BCMA) Antibody, anti-mouse, REAfinity™
Overview
Clone REA550 recognizes the mouse CD269 antigen, which is also known as B cell maturation protein BCMA. CD269 is a member of the TNF receptor superfamily. Its binding to BLyS and APRIL activates transcription factor NF-κB and stimulates IgM production by peripheral blood B cells. A soluble form of BCMA, which inhibits the proliferative activity of APRIL
in vitro, decreases tumor cell proliferation in nude mice. CD269 has been detected in immune organs such as spleen, thymus, bone marrow, and heart, as well as at lower levels in kidney and lung and is preferentially expressed in mature B lymphocytes.
Additional information: Clone REA550 displays negligible binding to Fc receptors.
Alternative names
TNFRSF17, Bcm, BCMA, Tnfrsf13, Tnfrsf13aDetailed product information
Technical specifications
| Clone | REA550 |
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| Clonality | monoclonal |
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| Isotype | recombinant human IgG1 |
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| Isotype control | REA Control Antibody, human IgG1 |
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| Host | human cell line |
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| Type of antibody | Primary antibodies, Recombinant antibodies |
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| Species | mouse |
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| Antigen | CD269 (BCMA) |
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| Alternative names of antigen | TNFRSF17, Bcm, BCMA, Tnfrsf13, Tnfrsf13a |
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| Molecular mass of antigen [kDa] | 20 |
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| Distribution of antigen | B cells |
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| Entrez Gene ID | 21935 |
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| RRID | AB_2656801, AB_2656802, AB_2656803, AB_2656804, AB_2656805, AB_2801983, AB_2656800, AB_2784095 |
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