Clone:
REA943
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
CCR9, Cmkbr10, GPR-9-6

Specifications for CD199 (CCR9) Antibody, anti-mouse, REAfinity™

Overview

Clone REA943 recognizes the mouse CD199 antigen, also known as CCR9. This chemokine receptor for CCL25 (TECK, thymus-expressed chemokine) is a member of the G-protein coupled receptor (GPCR) family. The main function of GPCR family members is to send signals into the cell after the activation of G-proteins. It is reported that CCR9 influences T cell development at several stages within the thymus. Furthermore, in peripheral blood, CCR9 is expressed by naive CD8 T cells, but not by naive CD4 T cells.
Additional information: Clone REA943 displays negligible binding to Fc receptors.

Alternative names

CCR9, Cmkbr10, GPR-9-6

Detailed product information

Technical specifications

CloneREA943
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD199 (CCR9)
Alternative names of antigenCCR9, Cmkbr10, GPR-9-6
Molecular mass of antigen [kDa]42
Distribution of antigenT cells, CD8+ T cells
Entrez Gene ID12769
RRIDAB_2727116, AB_2727117, AB_2727064, AB_2727119, AB_2727118, AB_2727114, AB_2727115

Resources for CD199 (CCR9) Antibody, anti-mouse, REAfinity™

References for CD199 (CCR9) Antibody, anti-mouse, REAfinity™

Publications

  1. Zaballos, A. et al. (1999) Cutting Edge: Identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J. Immunol. 162(10): 5671-5675
  2. Wurbel, M. A. et al. (2006) Complex regulation of CCR9 at multiple discrete stages of T cell development. Eur. J. Immunol. 36(1): 73-81

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