Clone:
REA1324
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
FCGR3A, FCGR3B, FcR-10, IGFR3, IMD20, FcRIII

Specifications for CD16 Antibody, anti-human, REAfinity™

Overview

Clone REA1324 recognizes the human CD16 antigen, a single-pass type I membrane protein which is also known as low affinity immunoglobulin gamma Fc region receptor III (FcRIII). CD16 is a 50–80 kDa glycoprotein that is expressed in two different isoforms. The transmembrane form (CD16A) is found on human NK cells, subsets of T cells, macrophages, and mast cells, while the glycosylphosphatidylinositol (GPI)-linked form (CD16b) is present on granulocytes. The human CD16 antigen is a low-affinity receptor for aggregated IgG. The transmembrane form plays a role in signal transduction, NK cell activation, and antibody-dependent cellular cytotoxicity. Clone REA1324 recognizes both CD16A and CD16B.
Additional information: Clone REA1324 displays negligible binding to Fc receptors.

Alternative names

FCGR3A, FCGR3B, FcR-10, IGFR3, IMD20, FcRIII

Detailed product information

Technical specifications

CloneREA1324
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD16
Alternative names of antigenFCGR3A, FCGR3B, FcR-10, IGFR3, IMD20, FcRIII
Distribution of antigenNK cells, monocytes, granulocytes, T cells, macrophages, neutrophils, spleen
RRIDAB_2904776

Resources for CD16 Antibody, anti-human, REAfinity™

Certificates

Please follow this
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to search for Certificates of Analysis (CoA) by lot number.

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