Clone:
VIMC6
Type of antibody:
Primary antibodies
Isotype:
mouse IgMκ
Alternative names:
FUT4, ELFT, FCT3A, FUC-TIV, FUTIV, Lex, SSEA-1, Lewis X

Specifications for CD15 antibodies

Overview

VIMC6 recognizes the human CD15 antigen which is expressed on human myelomonocytic cells. It is present on neutrophils, eosinophils, and some monocytes, masked on basophils but not on lymphocytes. The antigen is also expressed on Hodgkin/Reed-Sternberg cells. The CD15 antibody recognizes the carbohydrate structure 3-fucosyl-N-acetyl-lactosamine. This structure is also known as stage specific embryonic antigen 1 (SSEA-1) and a common surface marker for pluripotency on mouse ES and iPS cells. On human cells in contrast, SSEA-1 is expressed only on early differentiating cells. The CD15 antibody recognizes the SSEA-1 antigen in both species. For applications in ES and iPS research, the dilution recommended in the data sheet may need adjustment.

Applications

Reagent can be used for immunophenotyping by flow cytometry. Abnormal numbers of cells expressing this antigen or aberrant expression levels of the antigen can be expected in some disease states. It is important to understand the normal expression pattern for this antigen and its relationship to expression of other relevant antigens in order to perform appropriate analysis.
Expression of CD15 may be used as aid to diagnostic in the characterization of samples from individuals suspected with hematologic neoplasia.

Alternative names

FUT4, ELFT, FCT3A, FUC-TIV, FUTIV, Lex, SSEA-1, Lewis X

Detailed product information

Technical specifications

CloneVIMC6
Isotypemouse IgMκ
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD15
Alternative names of antigenFUT4, ELFT, FCT3A, FUC-TIV, FUTIV, Lex, SSEA-1, Lewis X
Distribution of antigenB cells, T cells, epithelial cells, granulocytes, Langerhans cells, monocytes, myeloid leukemia cells, basophils, eosinophils, neutrophils

Resources for CD15 antibodies

Certificates

Please follow this
link
to download the Certificate of Conformity (CoC) by lot number.