Name: CD105 Antibody, anti-human, REAlease®
Availability: InStock

Flow cytometry

Conjugate:	PerCP
Recommended dilution:	1:50
Tested:	QC tested
Products used:	130-124-556, 130-124-555

Multiparameter imaging cell screen

Conjugate:	FITC
Recommended dilution:	1:50
Fixation:	PFA
Tested:	during development
Products used:	130-115-290, 130-115-182
Compatible applications:	IF, IHC

Specifications for CD105 Antibody, anti-human,
REAlease
^®

Overview

Clone REAL218 is an antibody fragment derived from the full CD105 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.

Clone REAL218 recognizes the CD105 antigen, also known as endoglin, which serves as a receptor for the growth and differentiation factors TGF-β1 and TGF-β3. An epitope of CD105 is recognized by the SH-2 antibody, which was raised against human mesenchymal stromal cells (MSC) that show mesodermal differentiation capacity. Therefore, it can be used for studies on mesengenesis. CD105 is also expressed on mature endothelial cells and on some leukemic cells of B lymphoid and myeloid origin.

The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

ENG, END, HHT1, ORW1, Endoglin

Detailed product information

Technical specifications

Clone	REAL218
Clonality	monoclonal
Isotype control	Control Antibody
Host	cell line
Type of antibody	Releasable antibodies, Primary antibodies, Recombinant antibodies
Species	human
Antigen	CD105
Alternative names of antigen	ENG, END, HHT1, ORW1, Endoglin
Distribution of antigen	endothelial cells, B cells, myeloid cells
RRID	AB_2751248, AB_2783903, AB_2819672, AB_2819671, AB_2751254

References for CD105 Antibody, anti-human,
REAlease
^®

Publications

Bellón, T. et al. (1993) Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions. Eur. J. Immunol. 23(9): 2340-2345
Barry, F. P. et al. (1999) The monoclonal antibody SH-2, raised against human mesenchymal stem cells, recognizes an epitope on endoglin (CD105). Biochem. Biophys. Res. Commun. 265: 134-139
Majumdar, M. K. et al. (2000) Isolation, characterization, and chondrogenic potential of human bone marrow-derived multipotential stromal cells. J. Cell. Physiol. 185: 98-106

Applications

Specifications

Specifications for CD105 Antibody, anti-human,
REAlease
^®

Overview

Alternative names

ENG, END, HHT1, ORW1, Endoglin

Detailed product information

Technical specifications

Clone	REAL218
Clonality	monoclonal
Isotype control	Control Antibody
Host	cell line
Type of antibody	Releasable antibodies, Primary antibodies, Recombinant antibodies
Species	human
Antigen	CD105
Alternative names of antigen	ENG, END, HHT1, ORW1, Endoglin
Distribution of antigen	endothelial cells, B cells, myeloid cells
RRID	AB_2751248, AB_2783903, AB_2819672, AB_2819671, AB_2751254

References

References for CD105 Antibody, anti-human,
REAlease
^®

Publications

Bellón, T. et al. (1993) Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions. Eur. J. Immunol. 23(9): 2340-2345
Barry, F. P. et al. (1999) The monoclonal antibody SH-2, raised against human mesenchymal stem cells, recognizes an epitope on endoglin (CD105). Biochem. Biophys. Res. Commun. 265: 134-139
Majumdar, M. K. et al. (2000) Isolation, characterization, and chondrogenic potential of human bone marrow-derived multipotential stromal cells. J. Cell. Physiol. 185: 98-106

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CD105 Antibody, anti-human, REAlease®

CD105 Antibody, anti-human, REAlease®

Flow cytometry

Multiparameter imaging cell screen

Specifications for CD105 Antibody, anti-human, REAlease®

Overview

Alternative names

Detailed product information

Technical specifications

References for CD105 Antibody, anti-human, REAlease®

Publications

Specifications for CD105 Antibody, anti-human, REAlease®

Overview

Alternative names

Detailed product information

Technical specifications

References for CD105 Antibody, anti-human, REAlease®

Publications

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REAlease Support Kit

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About Miltenyi Biotec

CD105 Antibody, anti-human,
REAlease
^®

CD105 Antibody, anti-human,
REAlease
^®

Specifications for CD105 Antibody, anti-human,
REAlease
^®

References for CD105 Antibody, anti-human,
REAlease
^®

Specifications for CD105 Antibody, anti-human,
REAlease
^®

References for CD105 Antibody, anti-human,
REAlease
^®

Related products for
CD105 Antibody, anti-human,
REAlease
^®

Control Antibody,
REAlease
^®