Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:
Paired box protein Pax-3, HuP2, Pax3

Extended validation for PAX-3 Antibody, anti-human/mouse, REAfinity™


Epitope competition
In order to compare the epitope specificity of an antibody, the clone being used is compared with other known clones recognizing the same antigen in a competition assay.
Other clonesOverlap in epitope recognition with REA719
Cells were incubated with an excess of purified unconjugated PAX-3 (REA719) antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or completely different epitopes (-) of the marker.

Specifications for PAX-3 Antibody, anti-human/mouse, REAfinity™


Clone REA719 recognizes the human and mouse paired box protein PAX-3 antigen, a member of the paired box (PAX) gene family whose protein products are transcription factors involved in development. PAX-3 regulates cell proliferation, migration, and apoptosis and plays a role in neural development and myogenesis. Human and mouse PAX-3 share 98% amino acid sequence identity.
Additional information: Clone REA719 displays negligible binding to Fc receptors.

Alternative names

Paired box protein Pax-3, HuP2, Pax3

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse
Alternative names of antigenPaired box protein Pax-3, HuP2, Pax3
Molecular mass of antigen [kDa]53(same molecular weight for human and mouse/rat)
Entrez Gene ID5077, 18505
RRIDAB_2653155, AB_2653156, AB_2653157, AB_2653154

Resources for PAX-3 Antibody, anti-human/mouse, REAfinity™


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References for PAX-3 Antibody, anti-human/mouse, REAfinity™


  1. Tassabehji, M. et al. (1992) Waardenburg's syndrome patients have mutations in the human homologue of the Pax-3 paired box gene. Nature 355(6361): 635-636
  2. Begum, S. et al. (2005) Cell-type-specific regulation of distinct sets of gene targets by Pax3 and Pax3/FKHR. Oncogene 24(11): 1860-1872
  3. Wang, Q. et al. (2006)
    Functional analysis of alternative isoforms of the transcription factor PAX3 in melanocytes
    in vitro
    Cancer Res. 66(17): 8574-8580

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