Oligodeoxyribonucleotides containing CpG motifs (CpG ODNs) are widely used for activation of immune cells, such as human PBMCs, murine splenocytes or isolated immune cells, e.g., B cells and pDCs. They also activate signalling in TLR9-expressing recombinant cell lines.
ODN 2006 is a B-class ODN for activation of B cells , induction of Il-6 secretion and activation of NF-kB-signalling pathways.

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