CD8b antibodies, rat

CD8b antibodies, rat

Clone: REA222 | Dilution: 1:10
Clone REA222 recognizes rat CD8b, a member of the immunoglobulin superfamily also known as T cell surface glycoprotein Lyt-3. CD8b is expressed on cytotoxic T cells, thymocytes, and macrophages as a heterodimer with CD8a. CD8 identifies cytotoxic/suppressor T cells that interact with MHC class I bearing targets and plays a role in the process of T cell mediated killing. Flow cytometric analysis showed that CD8 T cells from lymph nodes or spleen of normal rats almost exclusively express the α/β heterodimer, regardless of the T cell receptor isotype. In contrast, natural killer cells carry only CD8a chains.
Additional information: Clone REA222 displays negligible binding to Fc receptors.

Alternative names

Cd8b1

Technical specifications

  • Antigen: CD8b
  • Clone: REA222
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Cd8b1
  • Entrez Gene ID: 24931
  • Molecular mass of antigen [kDa]: 21
  • Distribution of antigen: NK cells, granulocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Torres-Nagel, N. et al. (1992) Differential thymus dependence of rat CD8 isoform expression. Eur. J. Immunol. 22(11): 2841-2848
    2. Duplan, V. et al. (2007)
      Tracking antigen-specific CD8
      +
      T cells in the rat using MHC class I multimers.
      J. Immunol. Methods 320(1-2): 30-39
Product options: 14
130-103-321

CD8b-FITC, rat

9 µg in 300 µL (1)
EUR 31,00 
130-102-682

CD8b-FITC, rat

30 µg in 1 mL (1)
EUR 45,00 
130-103-322

CD8b-PE, rat

9 µg in 300 µL (1)
EUR 40,00 
130-102-683

CD8b-PE, rat

30 µg in 1 mL (1)
EUR 85,00 
130-103-323

CD8b-APC, rat

9 µg in 300 µL (1)
EUR 58,00 
130-102-684

CD8b-APC, rat

30 µg in 1 mL (1)
EUR 85,00 
130-103-320

CD8b-VioBlue, rat

9 µg in 300 µL (1)
EUR 85,00 
130-102-681

CD8b-VioBlue, rat

30 µg in 1 mL (1)
EUR 105,00 
130-103-324

CD8b-PE-Vio770, rat

9 µg in 300 µL (1)
EUR 71,00 
130-102-685

CD8b-PE-Vio770, rat

30 µg in 1 mL (1)
EUR 110,00 
130-103-325

CD8b-APC-Vio770, rat

9 µg in 300 µL (1)
EUR 76,00 
130-102-686

CD8b-APC-Vio770, rat

30 µg in 1 mL (1)
EUR 110,00 
130-102-120

CD8b-Biotin, rat

9 µg in 300 µL (1)
EUR 22,00 
130-101-974

CD8b-Biotin, rat

30 µg in 1 mL (1)
EUR 45,00 

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