CD21/CD35 antibodies, mouse

CD21/CD35 antibodies, mouse

Clone: REA800 | Dilution: 1:50
Clone REA800 recognizes an epitope shared by mouse CD21 and CD35, also known as CR2 and CR1. CD21 and CD35 are alternatively spliced transcripts from the Cr2 gene, which produce cell-surface proteins of 145 and 190 kDa, respectively. CD21 and CD35 are expressed on the majority of peripheral B lymphocytes, on the majority of resident peritoneal macrophages, on mast cells, activated granulocytes, and follicular dendritic cells. CD21 forms part of a signal transduction complex with CD19 and CD81, which are associated with the antigen receptor on B lymphocytes.
Additional information: Clone REA800 displays negligible binding to Fc receptors.

Alternative names

CR2, C3dR, C3b/C4b-R, CR1, EBV-R, Immune adherence receptor

Technical specifications

  • Antigen: CD21/CD35
  • Clone: REA800
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CR2, C3dR, C3b/C4b-R, CR1, EBV-R, Immune adherence receptor
  • Entrez Gene ID: 12902
  • Molecular mass of antigen [kDa]: 112
  • Distribution of antigen: B cells, basophils, dendritic cells, eosinophils, granulocytes, lymphocytes, macrophages, monocytes, neutrophils, NK cells, platelets, red blood cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected references

    1. Kozono, Y. et al. (1998) Cross-linking CD21/CD35 or CD19 increases both B7-1 and B7-2 expression on murine splenic B cells. J. Immunol. 160(4): 1565-1572
    2. Brockman, M. A. et al. (2006) Optimal long-term humoral responses to replication-defective herpes simplex virus require CD21/CD35 complement receptor expression on stromal cells. J. Virol. 80(14): 7111-7117
    3. Roozendaal, R. et al. (2007) Complement receptors CD21 and CD35 in humoral immunity. Immunol. Rev. 219: 157-166
Product options: 18
130-111-729

CD21/CD35-FITC, mouse

30 µg in 200 µL (1)
EUR 45,00 
130-111-651

CD21/CD35-FITC, mouse

150 µg in 1 mL (1)
EUR 130,00 
130-111-730

CD21/CD35-PE, mouse

30 µg in 200 µL (1)
EUR 85,00 
130-111-652

CD21/CD35-PE, mouse

150 µg in 1 mL (1)
EUR 245,00 
130-111-731

CD21/CD35-APC, mouse

30 µg in 200 µL (1)
EUR 85,00 
130-111-653

CD21/CD35-APC, mouse

150 µg in 1 mL (1)
EUR 245,00 
130-111-736

CD21/CD35-VioBlue, mouse

30 µg in 200 µL (1)
EUR 105,00 
130-111-658

CD21/CD35-VioBlue, mouse

150 µg in 1 mL (1)
EUR 300,00 
130-111-732

CD21/CD35-PE-Vio770, mouse

30 µg in 200 µL (1)
EUR 110,00 
130-111-654

CD21/CD35-PE-Vio770, mouse

150 µg in 1 mL (1)
EUR 320,00 
130-111-733

CD21/CD35-APC-Vio770, mouse

30 µg in 200 µL (1)
EUR 110,00 
130-111-655

CD21/CD35-APC-Vio770, mouse

150 µg in 1 mL (1)
EUR 320,00 
130-111-734

CD21/CD35-PerCP-Vio700, mouse

30 µg in 200 µL (1)
EUR 110,00 
130-111-656

CD21/CD35-PerCP-Vio700, mouse

150 µg in 1 mL (1)
EUR 320,00 
130-111-735

CD21/CD35-VioBright 515, mouse

30 µg in 200 µL (1)
EUR 155,00 
130-111-657

CD21/CD35-VioBright 515, mouse

150 µg in 1 mL (1)
EUR 455,00 
130-111-728

CD21/CD35-Biotin, mouse

30 µg in 200 µL (1)
EUR 45,00 
130-111-650

CD21/CD35-Biotin, mouse

150 µg in 1 mL (1)
EUR 130,00 

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