CD169 (Siglec-1) antibodies, human

CD169 (Siglec-1) antibodies, human

Clone: 7-239 | Dilution: 1:11
The monoclonal antibody 7-239 reacts with CD169, also known as siglec-1 or sialoadhesin, which is a type I transmembrane glycoprotein. It is the largest member of the siglec family, which are cell surface lectins that are able to bind to sialic acids and mediate interactions between proteins and carbohydrates. Siglec-1 is mainly expressed on tissue macrophages and dendritic cells and interacts with its counterreceptor on T cells, which has been identified as CD43.

Alternative names

Siglec-1, SN

Technical specifications

  • Antigen: CD169 (Siglec-1)
  • Clone: 7-239
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: Siglec-1, SN
  • Entrez Gene ID: 6614
  • Molecular mass of antigen [kDa]: 181
  • Distribution of antigen: bone marrow, macrophages, spleen
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. van den Berg, T. K. et al. (2001) Cutting Edge: CD43 functions as a T cell counterreceptor for the macrophage adhesion receptor Sialoadhesin (Siglec-1). J. Immunol. 166: 3637-3640
    2. Hartnell, A. et al. (2001) Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations. Blood 97: 288-296
    3. Crocker, P.R. et al. (2001) Siglecs, sialic acids and innate immunity. Trends Immunol. 22(6): 337-342
Product options: 14
130-098-656

CD169 (Siglec-1)-FITC, human

for 30
tests
(1)
EUR 100,00 
130-098-667

CD169 (Siglec-1)-FITC, human

for 100
tests
(1)
EUR 240,00 
130-098-647

CD169 (Siglec-1)-PE, human

for 30
tests
(1)
EUR 115,00 
130-098-654

CD169 (Siglec-1)-PE, human

for 100
tests
(1)
EUR 285,00 
130-098-643

CD169 (Siglec-1)-APC, human

for 30
tests
(1)
EUR 115,00 
130-098-645

CD169 (Siglec-1)-APC, human

for 100
tests
(1)
EUR 285,00 
130-098-638

CD169 (Siglec-1)-PE-Vio770, human

for 30
tests
(1)
EUR 130,00 
130-098-640

CD169 (Siglec-1)-PE-Vio770, human

for 100
tests
(1)
EUR 310,00 
130-101-278

CD169 (Siglec-1)-APC-Vio770, human

for 30
tests
(1)
EUR 130,00 
130-101-277

CD169 (Siglec-1)-APC-Vio770, human

for 100
tests
(1)
EUR 310,00 
130-101-508

CD169 (Siglec-1)-PerCP-Vio700, human

for 30
tests
(1)
EUR 130,00 
130-101-505

CD169 (Siglec-1)-PerCP-Vio700, human

for 100
tests
(1)
EUR 310,00 
130-098-671

CD169 (Siglec-1)-Biotin, human

for 30
tests
(1)
EUR 100,00 
130-098-674

CD169 (Siglec-1)-Biotin, human

for 100
tests
(1)
EUR 240,00 

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