Anti-FPRL1/FPR2 antibodies, human

Anti-FPRL1/FPR2 antibodies, human

Clone: REA663 | Dilution: 1:50
Clone REA663 recognizes the human FPRL1 antigen, a G-protein coupled receptor (GPCR), also known as FPR2 or N-formyl peptide receptor 2. FPRL1 mediates chemotaxis, degranulation, and the respiratory burst. It interacts with lipoxin A4, which is involved in immunomodulatory and anti-inflammatory actions. FPRL1 is expressed on mononuclear phagocytes and microglial cells.
Additional information: Clone REA663 displays negligible binding to Fc receptors.

Alternative names

FPR2, ALXR, RFP, HM63

Technical specifications

  • Antigen: FPRL1/FPR2
  • Clone: REA663
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: FPR2, ALXR, RFP, HM63
  • Entrez Gene ID: 2358
  • Molecular mass of antigen [kDa]: 39
  • Distribution of antigen: microglia, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
  • Selected references

    1. Takano, T. et al. (1997) Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors. J. Exp. Med. 185(9): 1693-1704
    2. Murphy, P. M. et al. (1992) A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family. J. Biol. Chem. 267(11): 7637-7643
Product options: 2
for 30
tests
(1)
EUR 125,00 
for 100
tests
(1)
EUR 295,00 

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