Anti-Cyclin A2 antibodies, human

Anti-Cyclin A2 antibodies, human

Clone: REA951 | Dilution: 1:50
Clone REA951 recognizes the human protein cyclin A2, which belongs to the cyclin family, that members function as regulators for the activity of the cyclin-dependent protein kinases. Cyclin A plays a role in the regulation of the cell cycle and is important for S and M phase, thus cyclin A is used as a marker for actively proliferating cells and for cells in S phase. It is found in dividing cells, e.g., several leukemic cell lines as well as in testis and brain. Clone REA951 does not cross-react with other cyclins or cyclin A1.
Additional information: Clone REA951 displays negligible binding to Fc receptors.

Technical specifications

  • Antigen: Cyclin A2
  • Clone: REA951
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Entrez Gene ID: 890
  • Molecular mass of antigen [kDa]: 34
  • Distribution of antigen: brain, testicle
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Vio515
  • Selected references

    1. Pagano, M. et al. (1992) Cyclin A is required at two points in the human cell cycle. EMBO J. 11(3): 961-971
    2. Furuno, N. et al. (1999) Human cyclin A is required for mitosis until mid prophase. J. Cell Biol. 147(2): 295-306
    3. Geley, S. et al. (2001) Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. J. Cell Biol. 153(1): 137-148
Product options: 8
for 30
tests
(1)
EUR 105,00 
for 100
tests
(1)
EUR 245,00 
for 30
tests
(1)
EUR 125,00 
for 100
tests
(1)
EUR 295,00 
for 30
tests
(1)
EUR 125,00 
for 100
tests
(1)
EUR 295,00 
for 30
tests
(1)
EUR 125,00 
for 100
tests
(1)
EUR 300,00 

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