CD180 (RP105) Antibody, anti-human
Clone:
MHR73-11
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC, MICS, IF, IHC
Alternative names:
LY64, Ly78, RP105

Specifications for CD180 (RP105) Antibody, anti-human

Overview

The monoclonal antibody MHR73-11 recognizes human CD180, also known as RP105, which is a 105 kDa type 1 transmembrane protein of the toll-like receptor (TLR) family. The extracellular domain of CD180 is associated with MD-1, which forms the cell surface complex RP105/MD-1. Together with TLR4, it mediates B cell recognition and signaling of LPS. CD180 is expressed on mature B cells in mantle zones, on monocytes, macrophages, and dendritic cells.

Alternative names

LY64, Ly78, RP105

Detailed product information

Technical specifications

CloneMHR73-11
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman, non-human primate
Cross-reactivity
rhesus monkey (
Macaca mulatta
)
,
cynomolgus monkey (
Macaca fascicularis
)
,
olive baboon (
Papio anubis
)
AntigenCD180 (RP105)
Alternative names of antigenLY64, Ly78, RP105
Molecular mass of antigen [kDa]72
Distribution of antigenB cells, dendritic cells, macrophages, monocytes, plasma cells
Entrez Gene ID4064
RRIDAB_2655689, AB_2655690, AB_2655691, AB_2655692, AB_2655693, AB_2655694, AB_2655688

Resources for CD180 (RP105) Antibody, anti-human

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD180 (RP105) Antibody, anti-human

Publications

  1. Miura, Y. et al. (1998) RP105 Is associated with MD-1 and transmits an activation signal in human B cells. Blood 92: 2815 - 2822
  2. Divanovic, S. et al. (2005) Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. Nat Immunol 6(6): 571-578
  3. Ogata, H. et al. (2000) The toll-like receptor protein Rp105 regulates lipopolysaccharide signaling in B cells. J. Exp. Med. 192: 23-30

Related products for
CD180 (RP105) Antibody, anti-human

4 products available
 

Tandem Signal Enhancer, human

The Tandem Signal Enhancer, human increases binding specificity of tandem dye–conjugated antibodies ...

 

Isotype Control Antibody, mouse IgG1

The Mouse IgG1 isotype control antibody clone IS5-21F5 is specific for keyhole limpet hemocyanin ...

130-059-901

FcR Blocking Reagent, human

The FcR Blocking Reagent was developed to increase the specificity of immunofluorescent staining ...

130-097-900

MACS
®
Comp Bead Kit, anti-mouse Igκ

The MACS® Comp Bead Kits have been developed for optimal compensation of the fluorescence spillover ...

Seems like you are coming from USA!
Do you want to visit our website in your country?

Copyright © 2023 Miltenyi Biotec and/or its affiliates. All rights reserved.