Clone:
REAL815
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
Villin-1, VIL1, VIL

Specifications for Villin Antibody, anti-human, REAdye_lease™

Overview

Clone REAL815 is an antibody fragment derived from the full Villin antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL815 recognizes human Villin protein, also known as Villin-1, a member of a family of calcium-regulated actin-binding proteins encoded by the VIL1 gene. This protein represents a dominant part of the brush border cytoskeleton and plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Villin regulates the intestinal epithelial cell morphology, cell invasion, cell migration and apoptosis and enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, chemotaxis and wound repair.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

Villin-1, VIL1, VIL

Detailed product information

Technical specifications

CloneREAL815
Clonalitymonoclonal
Isotype controlControl Antibody
Hosthuman cell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenVillin
Alternative names of antigenVillin-1, VIL1, VIL

Resources for Villin Antibody, anti-human, REAdye_lease™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for Villin Antibody, anti-human, REAdye_lease™

Publications

  1. Wang, Y. et al. (2008) A novel role for villin in intestinal epithelial cell survival and homeostasis. J. Biol. Chem. 283(14): 9454-9464
  2. Srivatsa, S. et al. (2017) EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patient. Gastroenterology 153(1): 178-190
  3. Izdebska, M. et al. (2020) Involvement of Actin and Actin-Binding Proteins in Carcinogenesis. Cells 9(10): 2245

Related products for
Villin Antibody, anti-human, REAdye_lease™

1 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?