CD91 antibodies, human

CD91 antibodies, human

Clone: REA709 | Dilution: 1:50
Clone REA709 recognizes the human CD91 antigen, also known as low density lipoprotein receptor-related protein 1 (LRP1), alpha-2-macroglobulin receptor (A2MR), or apolipoprotein E receptor (APOER). CD91 is a type 1 transmembrane protein receptor protein which is located in the plasma membrane of cells involved in receptor-mediated endocytosis. Furthermore, CD91 plays a role in lipoprotein metabolism and cell motility, and different diseases, such as neurodegenerative diseases, atherosclerosis, and cancer. CD91 is mainly expressed in liver, brain, and lung.
Additional information: Clone REA709 displays negligible binding to Fc receptors.

Alternative names

LRP-1, A2MR, APOER

Technical specifications

  • Antigen: CD91
  • Clone: REA709
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: LRP-1, A2MR, APOER
  • Entrez Gene ID: 4035
  • Molecular mass of antigen [kDa]: 503
  • Distribution of antigen: liver, brain, lung cancer cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PerCP-Vio700, Biotin, VioBright FITC, PE, APC, PE-Vio770
  • Selected references

    1. Herz, J. et al. (1988) Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. EMBO J. 7(13): 4119-4127
    2. Lillis, A.P. et al. (2005) Beyond endocytosis: LRP function in cell migration, proliferation and vascular permeability. J. Thromb. Haemost. 3(8): 1884-1993
    3. Etique, N. et al. (2013) LRP-1: a checkpoint for the extracellular matrix proteolysis. Biomed Res Int : 152-163
Product options: 12
for 30
tests
(1)
EUR 100.00
for 100
tests
(1)
EUR 240.00
130-111-412

CD91-PE, human

for 30
tests
(1)
EUR 90.00
130-111-225

CD91-PE, human

for 100
tests
(1)
EUR 220.00
130-111-413

CD91-APC, human

for 30
tests
(1)
EUR 90.00
130-111-226

CD91-APC, human

for 100
tests
(1)
EUR 220.00
for 30
tests
(1)
EUR 100.00
for 100
tests
(1)
EUR 240.00
for 30
tests
(1)
EUR 100.00
for 100
tests
(1)
EUR 240.00
for 30
tests
(1)
EUR 75.00
for 100
tests
(1)
EUR 185.00

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