CD229 (Ly-9) antibodies, mouse

CD229 (Ly-9) antibodies, mouse

Clone: REA273 | Dilution: 1:10
Clone REA273 recognizes both mouse CD229 antigen alleles, Ly9.1 and Ly9.2. CD229 is a glycoprotein of the SLAM family also known as Ly9 or SLAMF3 which is a homophilic cell surface receptor present on a variety of immune cell types including T cells, B cells, NK cells, and thymocytes. It has been shown to interact with the adaptor proteins, SLAM-associated protein and EAT-2. CD229 is highly expressed on innate-like lymphocytes such as iNKT cells and in contrast to SLAMF1 and SLAMF6, CD229 plays a negative rather than a positive role in the signaling pathways required for innate-like lymphocyte development in the thymus.
Additional Information: Clone REA273 displays negligible binding to Fc receptors.

Alternative names

Ly-9, Lgp100, SLAMF3, T100, Lymphocyte antigen 9

Technical specifications

  • Antigen: CD229 (Ly-9)
  • Clone: REA273
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Ly-9, Lgp100, SLAMF3, T100, Lymphocyte antigen 9
  • Entrez Gene ID: 17085
  • Molecular mass of antigen [kDa]: 68
  • Distribution of antigen: B cells, T cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Romero, X. et al. (2005) CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. J. Immunol. 174(11): 7033-7042
    2. Sintes, J. et al. (2013)
      Ly9 (CD229), a SLAM family receptor, negatively regulates the development of thymic innate memory-like CD8
      +
      T and invariant NKT cells.
      J. Immunol. 190: 21-26
    3. Tovar, V. et al. (2000) Gene structure of the mouse leukocyte cell surface molecule Ly9. Immunogenetics 51(10): 788-793
Product options: 12
9 µg in 300 µL (1)
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30 µg in 1 mL (1)
EUR 35.00
9 µg in 300 µL (1)
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30 µg in 1 mL (1)
EUR 65.00
9 µg in 300 µL (1)
EUR 32.00
30 µg in 1 mL (1)
EUR 65.00
9 µg in 300 µL (1)
EUR 41.00
30 µg in 1 mL (1)
EUR 85.00
9 µg in 300 µL (1)
EUR 42.00
30 µg in 1 mL (1)
EUR 85.00
9 µg in 300 µL (1)
EUR 12.00
30 µg in 1 mL (1)
EUR 35.00

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