CD134 (OX40) antibodies, mouse

CD134 (OX40) antibodies, mouse

Clone: OX-86 | Dilution: 1:10
The CD134 antigen, also known as OX40 receptor, is a 50 kDa type I membrane glycoprotein of the TNF/NGF receptor superfamily. It is expressed on activated mouse T cells and B cells. The OX40 receptor binds to the OX40 ligand (CD252) to provide a costimulatory signal which is independent of CD28. The OX-86 monoclonal antibody does not block this interaction and is reported to provide costimulation signals to T cells.

Alternative names

TNFRSF4, Ly-70, OX-40, Txgp1l, Txgp1, ACT35

Technical specifications

  • Antigen: CD134 (OX40)
  • Clone: OX-86
  • Isotype: rat IgG1κ
  • Isotype control: Rat IgG1 – isotype control antibodies
  • Alternative names of antigen: TNFRSF4, Ly-70, OX-40, Txgp1l, Txgp1, ACT35
  • Entrez Gene ID: 22163
  • Molecular mass of antigen [kDa]: 28
  • Distribution of antigen: B cells, endothelial cells, fibroblasts, lymphocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, Biotin, PE
  • Selected references

    1. al-Shamkhani, A. et al. (1996) OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand. Eur. J. Immunol. 26(8): 1695-1699
    2. Kjaergaard, J. et al. (2001) Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor. J. Immunol. 167: 6669-6677
    3. Akiba, H. et al. (1999) CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. J. Immunol. 162(12): 7058-7066
Product options: 3
30 µg in 1 mL (1)
EUR 65.00
30 µg in 1 mL (1)
EUR 65.00
30 µg in 1 mL (1)
EUR 35.00

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