CD105 antibodies, human

CD105 antibodies, human

Clone: REA794 | Dilution: 1:50
Clone REA794 recognizes the CD105 antigen, also known as endoglin, which serves as a receptor for the growth and differentiation factors TGF-β1 and TGF-β3. An epitope of CD105 is recognized by the SH-2 antibody, which was raised against human mesenchymal stromal cells (MSC) that show mesodermal differentiation capacity. Therefore, it can be used for studies on mesengenesis. CD105 is also expressed on mature endothelial cells and on some leukemic cells of B lymphoid and myeloid origin.
Additional information: Clone REA794 displays negligible binding to Fc receptors.

Alternative names

ENG, END, HHT1, ORW1, Endoglin

Technical specifications

  • Antigen: CD105
  • Clone: REA794
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ENG, END, HHT1, ORW1, Endoglin
  • Entrez Gene ID: 2022
  • Molecular mass of antigen [kDa]: 68
  • Distribution of antigen: bone marrow, endothelial cells, leukemia cells, mesenchymal stem cells, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Bellón, T. et al. (1993) Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions. Eur. J. Immunol. 23(9): 2340-2345
    2. Barry, F. P. et al. (1999) The monoclonal antibody SH-2, raised against human mesenchymal stem cells, recognizes an epitope on endoglin (CD105). Biochem. Biophys. Res. Commun. 265: 134-139
    3. Majumdar, M. K. et al. (2000) Isolation, characterization, and chondrogenic potential of human bone marrow-derived multipotential stromal cells. J. Cell. Physiol. 185: 98-106
Product options: 18
for 30
tests
(1)
EUR 75.00
for 100
tests
(1)
EUR 185.00
130-112-321

CD105-PE, human

for 30
tests
(1)
EUR 90.00
130-112-163

CD105-PE, human

for 100
tests
(1)
EUR 220.00
130-112-324

CD105-APC, human

for 30
tests
(1)
EUR 90.00
130-112-166

CD105-APC, human

for 100
tests
(1)
EUR 220.00
for 30
tests
(1)
EUR 95.00
for 100
tests
(1)
EUR 230.00
for 30
tests
(1)
EUR 100.00
for 100
tests
(1)
EUR 240.00
for 30
tests
(1)
EUR 100.00
for 100
tests
(1)
EUR 240.00
for 30
tests
(1)
EUR 100.00
for 100
tests
(1)
EUR 240.00
for 30
tests
(1)
EUR 100.00
for 100
tests
(1)
EUR 240.00
for 30
tests
(1)
EUR 75.00
for 100
tests
(1)
EUR 185.00

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